By Debi Wimberley Certified Cannabis Educator and Founder of the Effective Cannabis Newsletter

Have you ever found yourself lost in the vast world of skin care products, wondering which one holds the key to your skin’s happiness? From rashes and acne, burns and cuts to dry or wrinkled skin, choices can be overwhelming. But what if there’s a natural solution hidden in plain sight, thanks to your body’s superhero: the Endocannabinoid System (ECS)?

Understanding Skin and Cannabinoids: A Perfect Match

Your Skin Endocannabinoid System

Exploring the intricate network of the Endocannabinoid System in the skin sheds light on its vital functions, including melanin production, wound healing, barrier function, and pain perception. This system, comprising cannabinoid receptors CB1 and CB2, forms the basis for the therapeutic potential of cannabinoids in skin care. To dive deeper into the critical role of your ECS, see “The Endocannabinoid System of the Skin” [1] [2].

The Science Behind Cannabis: How Cannabinoids Transform Skin Health

Research shows that cannabinoids [3] have a remarkable impact on skin care. To unravel the secrets of the ECS, discover the therapeutic potential of CBD, CBG, and even THC and how they can revolutionize your skincare routine.

CBD, CBG, and THC: Your Skin’s New Best Friends

Let’s explore the unique qualities of CBD, CBG, and THC and uncover their magic in action:

CBD (Cannabidiol)

CBD has gained significant attention in the realm of skincare due to its potential benefits [4] in protecting the skin. It is rich in antioxidants and possesses anti-inflammatory properties, making it a promising addition to skincare routines. Here are some of the benefits. 

Antioxidants and Anti-Inflammatory Properties

• Reduction of Free Radicals: CBD decreases the production of free radicals (5) in the skin, reducing oxidative stress and protecting skin cells from damage.
• Protection of Antioxidants: CBD protects non-enzymatic antioxidants (6) in the skin, enhancing the skin’s overall defense system. CBD’s antioxidant properties protect the skin from environmental stressors, contributing to a more youthful appearance. Studies [7] like “Topical cannabidiol (CBD) in skin pathology - A comprehensive review and prospects for new therapeutic opportunities“ highlight CBD’s protective benefits against oxidative stress.
• Inflammation Reduction: CBD interacts with receptors in the skin’s ECS, reducing inflammation. Studies [8] such as “Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders” have demonstrated CBD’s ability to inhibit excessive sebum production, making it effective against acne [9].

Efficacy Against Skin Disorders

Preclinical evidence suggests that topical application of CBD is efficacious for various skin disorders such as eczema [10] and psoriasis [11] indicating its therapeutic potential for maintaining skin health.

Combatting Dryness, Itching, and Aging

CBD’s anti-inflammatory properties prove beneficial in alleviating symptoms of skin conditions like eczema and psoriasis. By soothing irritation and promoting skin repair, CBD addresses dryness and itching. Moreover, the presence of vitamins A, C, D, and E in CBD oil contributes to skin rejuvenation, acting as antioxidants and promoting overall skin health. CBD’s ability to tighten the skin reduces wrinkles [12] and promotes a youthful appearance.

CBG (Cannabigerol)

CBG  is emerging as a compelling player in the world of skincare due to its potential to deliver a range of benefits. Research (13) suggests that it may offer unique advantages in promoting skin health and vitality. From its antioxidative properties to anti-inflammatory and antibacterial, CBG offers relief from skin conditions exacerbated by bacterial infections. As we delve deeper into the specifics, it becomes clear that CBG has the potential to be a valuable addition to your skincare routine.

Anti-Inflammatory and Antibacterial Properties

• Reducing Inflammation: Similar to THC, CBG possesses robust anti-inflammatory (13) properties. It provides effective relief to individuals suffering from symptoms such as inflammation, redness, and swelling.
• Bacterial Defense: CBG’s antibacterial (14) properties make it invaluable for addressing skin conditions exacerbated by bacterial (15) infections, such as acne. By combating harmful bacteria, CBG promotes a healthier skin environment.

Neuroprotective Effects

• Soothing Irritation: CBG’s potential neuroprotective (16) effects can help soothe irritated skin. This calming property is particularly beneficial for individuals dealing with conditions like dermatitis, offering relief from irritation and discomfort.

THC (Tetrahydrocannabinol)

You might be surprised to hear that THC, which is commonly only known for its intoxicating effect is proving to be beneficial in skincare. Recent research suggests it might have untapped potential and exhibits some intriguing properties that could have positive effects on the skin. Let's look into its analgesic effects, easing discomfort and itching while stimulating essential nutritional support.
You'll discover the surprising ways in which THC may offer unique advantages in skincare.

Anti-Inflammatory Benefits

• Reduction of Inflammation: THC interacts with CB1 and CB2 receptors in the skin’s ECS, significantly reducing inflammation (17). This property is invaluable for individuals battling skin conditions like psoriasis and eczema, where inflammation is a prominent symptom.

Analgesic Effects

• Pain Relief: THC is a potent pain reliever by engaging with the ECS, making it a valuable ally for skin conditions (18) that cause discomfort, itching, or pain.

Appetite Stimulation

• Nutritional Support: For skin conditions linked to malnutrition or eating disorders, THC’s ability to stimulate appetite (19) can be a game-changer. Proper nutrition is fundamental for healthier skin, and THC can assist patients in getting the nutrients they need.

Harnessing the Power: How to Use CBD, CBG and THC for Skin Conditions

When it comes to managing various skin conditions, the dynamic trio of CBD, CBG, and THC brings some fantastic perks to the table when it comes to your skin. CBD's anti-inflammatory and antioxidant properties make it a go-to choice for soothing and revitalizing the skin. CBG, with its antibacterial and oil-regulating abilities, provides a natural way to balance skin health. THC, while known for its pain-relieving qualities, also plays a role in regenerating and rejuvenating the skin.  

Explore the practical side of skin care. Learn how to incorporate cannabinoid-infused creams, lotions, and balms into your routine. These targeted solutions offer localized relief, promoting healthier, clearer, and more radiant skin. Unlock the natural healing potential of cannabis topicals and nurture your skin the way nature intended.

Choosing from the Aisles Cannabis Topicals

When you're on the hunt for a topical to pamper your skin, it's essential to be a discerning consumer. Here's the deal: not all topicals are created equal.

So, here's what to keep in mind:

Some topicals have been whipped up for muscle aches and joint pain, not your sensitive skin.

You want to steer clear of irritating terpenes that don't play well with sensitive skin, especially if you're dealing with issues like eczema. In the image below you will find a list of terpenes that play harmoniously with your skin.

And now, a word about the wide world of hemp-based products. They're all over the internet and in nearly every store. There's not much oversight, so you've got to be your own detective. These products might lack consistency, and some of them could have uninvited companions like pesticides or metals.

Future Prospects 

As scientific exploration into cannabinoids continues, the potential for treating various skin conditions appears promising. With cannabinoids demonstrating efficacy in both topical and systemic applications, the future holds exciting possibilities. Ongoing research aims to uncover additional benefits.

The emergence of infused beauty products prompts questions about their efficacy. Research suggests that CBD, CBG, and THC, with their anti-inflammatory properties, offer a range of benefits, from acne treatment to anti-aging solutions. A new review (20) published in Molecules "Therapeutic Potential of Minor Cannabinoids in Dermatological Diseases—A Synthetic Review"  shows there are many other cannabinoids in the Cannabis plant that are worth consideration as well.

A Final Perspective

The therapeutic benefits of Cannabis topicals extend beyond mere pain relief, offering a holistic approach to skin health. Imagine these topicals as a diverse toolkit, each option uniquely suited to cater to your specific needs. Whether it’s CBD, CBG, and/or THC lotions, creams, oils, or salves, there’s a perfect helper waiting for you.

Your only hurdle? The delightful adventure of experimenting with them all! With research into the effects of topical Cannabis on the rise and interest ever increasing, this is just the beginning. The topical future is so bright; you might need sunglasses, or better yet, gear up for the journey with a visor! 

Stay tuned for further discoveries in this dynamic field. Don’t miss out on the transformative outcomes that integrating cannabinoids into your skincare routine could bring. The future of skincare is here, and it’s high time to experience its remarkable benefits firsthand!

So, Are You Ready to Embark on Your Journey With Topical Cannabis Relief?

Take the first step by exploring our online directory of certified Cannabis educators, coaches, and medical professionals. Once you’ve found the perfect match for your needs, connect with them and unlock the gift of healing tailored just for you! Your path to your skincare routine starts here.

References

1.“The Endocannabinoid System of the Skin.” YouTube, Friends of the Farm Lecture Series, 16 Dec. 2021, www.youtube.com/watch?v=og9f1o1_ijw. https://www.youtube.com/watch?v=og9f1o1_ijw

2. Bíró, Tamás et al. “The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities.” Trends in pharmacological sciences vol. 30,8 (2009): 411-20. doi:10.1016/j.tips.2009.05.004

3. Ramer, Robert, and Burkhard Hinz. “Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases.” Cells, vol. 11, no. 24, Dec. 2022, p. 4102. Crossref, https://doi.org/10.3390/cells11244102. 

4. Ferreira, B.P., Costa, G., Mascarenhas-Melo, F. et al. Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety. Phytochem Rev 22, 781–828 (2023). https://doi.org/10.1007/s11101-023-09860-5

5. Pereira, Sónia R et al. “Cannabidiol modulation of oxidative stress and signalling.” Neuronal signaling vol. 5,3 NS20200080. 24 Aug. 2021, doi:10.1042/NS20200080

6. Atalay, Sinemyiz, et al. “Antioxidative and Anti-Inflammatory Properties of Cannabidiol.” Antioxidants, vol. 9, no. 1, Dec. 2019, p. 21. Crossref, https://doi.org/10.3390/antiox9010021.

7. Makhakhe, Lehlohonolo. “Topical cannabidiol (CBD) in skin pathology - A comprehensive review and prospects for new therapeutic opportunities.” South African family practice : official journal of the South African Academy of Family Practice/Primary Care vol. 64,1 e1-e4. 30 May. 2022, doi:10.4102/safp.v64i1.5493

8.  Baswan, Sudhir M et al. “Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders.” Clinical, cosmetic and investigational dermatology vol. 13 927-942. 8 Dec. 2020, doi:10.2147/CCID.S286411

9. Ziqi Jiang, Shanglin Jin, Xiaoyao Fan, Ke Cao, Ye Liu, Xuan Wang, Ying Ma & Leihong Xiang (2022) Cannabidiol Inhibits Inflammation Induced by Cutibacterium acnes-Derived Extracellular Vesicles via Activation of CB2 Receptor in Keratinocytes, Journal of Inflammation Research, 15:, 4573-4583, DOI: 10.2147/JIR.S374692

10. “Eczema Stats.” National Eczema Association, 5 Sept. 2023, nationaleczema.org/research/eczema-facts/. https://nationaleczema.org/research/eczema-facts/

11. Wroński, Adam et al. “Phytocannabinoids in the Pharmacotherapy of Psoriasis.” Molecules (Basel, Switzerland) vol. 28,3 1192. 25 Jan. 2023, doi:10.3390/molecules28031192

12. Few, Julius et al. “A Single-Center Study Evaluating the Effects of a Novel Retinol and Cannabidiol Combination Topical on Facial Skin.” Aesthetic surgery journal. Open forum vol. 4 ojac002. 27 Jan. 2022, doi:10.1093/asjof/ojac002

13. Perez, Eduardo, et al. “In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties.” Molecules, vol. 27, no. 2, Jan. 2022, p. 491. Crossref, 

14. Aqawi, Muna, et al. “The Antibacterial Effect of Cannabigerol toward Streptococcus Mutans Is Influenced by the Autoinducers 21-CSP and AI-2.” Biomedicines, vol. 11, no. 3, Feb. 2023, p. 668. Crossref, https://doi.org/10.3390/biomedicines11030668.

15. Luz-Veiga, Mariana, et al. “Cannabidiol and Cannabigerol Exert Antimicrobial Activity without Compromising Skin Microbiota.” International Journal of Molecular Sciences, vol. 24, no. 3, Jan. 2023, p. 2389. Crossref, https://doi.org/10.3390/ijms24032389.

16. di Giacomo, Viviana et al. “Antioxidant and Neuroprotective Effects Induced by Cannabidiol and Cannabigerol in Rat CTX-TNA2 Astrocytes and Isolated Cortexes.” International journal of molecular sciences vol. 21,10 3575. 18 May. 2020, doi:10.3390/ijms21103575

17. Martins, Ana M et al. “Cannabis-Based Products for the Treatment of Skin Inflammatory Diseases: A Timely Review.” Pharmaceuticals (Basel, Switzerland) vol. 15,2 210. 9 Feb. 2022, doi:10.3390/ph15020210

18. Bruni, Natascia, et al. “Cannabinoid Delivery Systems for Pain and Inflammation Treatment.” Molecules, vol. 23, no. 10, Sept. 2018, p. 2478. Crossref, https://doi.org/10.3390/molecules23102478.

19. Hull, Michael, and Examine.com. “The Science behind Munchies: Cannabis and Your Appetite.” Examine, 31 Jan. 2023, examine.com/articles/cannabis-munchies/. 

20. Minor Cannabinoids https://www.mdpi.com/1420-3049/28/16/6149 Kwiecień, Emilia, and Dorota Kowalczuk. “Therapeutic Potential of Minor Cannabinoids in Dermatological Diseases—A Synthetic Review.” Molecules, vol. 28, no. 16, Aug. 2023, p. 6149. Crossref, https://doi.org/10.3390/molecules28166149.  

About Debi Wimberley:

Debi Wimberley is a staunch, tireless, and caring advocate for Medical Cannabis education and self-empowerment in healthy living. A survivor of decades of chronic, debilitating pain and lung disease, she never gave up hope, even when doctors bluntly declared there was nothing more they could do. Taking matters into her own hands, Debi drew on her background in medical technology, oncology, and hospitals as tools to learn, understand and thrive. Being adaptive and agile allowed her to obtain certifications in Medical Cannabis applications, Patient Care and become a certified professional communicator and content creator specializing in Cannabis. Debi is blazing new territory. Her mission is to centralize quality, accurate, fact-based education through collaborative work with other certified Cannabis educators, health coaches, and professionals. 

Effective Cannabis Newsletter is a platform to educate on the vital role of the Endocannabinoid System (ECS) in one's health. The information is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. All content, including text, graphics, images, and information, contained in or available through this newsletter is for general information purposes only. It is not medical advice; it is health awareness.